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In particular, it has been shown [10] that the SAR of such assembly depends substantially on the mean nanoparticle diameter, among other factors.
The dependence of the specific absorption rate on the mean nanoparticle diameter is retained with an increase of η, but becomes less pronounced.
The dependence of the assembly SAR on the mean nanoparticle diameter is retained with increase of η, but becomes less pronounced.
Furthermore, if we see the trend of change in mean nanoparticle diameter from Fig. 5d, it is exactly the same for both measurement techniques indicating good agreement between the results from both techniques.
Due to this, SAXS measures an agglomerate as one big particle which gives a higher volume and consequently increases the mean nanoparticle diameter in the volume size distribution measurement.
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The mean nanoparticle diameters showed in Fig. 5a c were 9.84, 7.31, and 6.06 nm, respectively, from TEM images, while for the same samples analyzed by SAXS measurement, the mean nanoparticle diameters were 16.54, 13.76, and 12.16 nm, respectively.
The measured mean nanoparticle diameters in SAXS technique and from analysis of TEM images varied from each other for the same samples.
Experimental responses of a total of 15 formulations resulted in mean nanoparticle diameters ranging from 394 to 588 nm, with polydispersity index from 0.77 to 1.10, zeta potential values ranging from −36.6 to −44.5 mV, and entrapment efficiency of insulin was over 85%.
nanoparticle diameter (nm).
Figure 7 Nanoparticles' mean diameter.
The nanoparticles' mean diameter was determined by counting about 200 randomly chosen particles from the relevant TEM images [30, 31] and the particles are with an average diameter of 4 nm for all Rh content catalyst, and 6 nm for Pt/C.
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