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Death was observed only in Jurkat cells suggesting that 10-ns EP may selectively kill cells within a heterogeneous tissue.
Up to now, current treatment for HNSCC may selectively kill the differentiated cancer cells, producing tumor regression while sparing the CSC, leading to regrowth and relapse.
Therefore, β-lapachone may selectively kill cancer cells that target NQO1.
Thus, targeting the mitotic checkpoint and chromosome alignment simultaneously may selectively kill tumor cells.
Interestingly, metformin may selectively kill cancer stem cells, since increased dependency on Warburg-like aerobic glycolysis (hyperglycolytic phenotype) is critical to sustain CSCs stemness and immortality.
Other in vitro studies suggest that metformin may selectively kill cancer stem cells and enhance effectiveness of breast cancer treatment regimens (85– 85).
Similar(51)
Hartwell et al. (1997) posited that cancer cells harboring specific somatic mutations may be selectively killed by targeting or inhibiting a second unlinked gene target through a synthetic lethal (SL) paradigm.
High-specificity-designed proteins that selectively kill target cells may provide an advantage over the toxic compounds used in current generation antibody-drug conjugates.
The next generation of radioimmunotherapy may lie with alpha-emitting radioisotopes that can selectively kill targeted cancer cells.
The elucidation of unique DNA repair defects in the highly mutable cells from a tumor may help in the design of targeted chemotherapies to selectively kill those cells while sparing normal cells.
This strongly suggests that the potent anticancer effects induced by cardiac glycosides in mice transplanted with human cancer cells may be an experimental artifact caused by their ability to selectively kill human cells versus rodent cells rather than by their ability to kill human cancer cells versus human nonmalignant cells.
Related(20)
may selectively enhance
may selectively fine
may selectively diminish
may selectively transport
may selectively be
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may selectively suppress
may selectively accumulate
may selectively promote
may selectively eat
may selectively occur
may selectively release
may selectively recruit
may selectively lose
may selectively block
may selectively affect
may selectively choose
may selectively cite
may selectively decrease
may selectively contact
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