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Sensory feedback to facilitate motor function may require simultaneous or timed responses across separate digits to recreate perceptions of slip as well as encoding of intensity variations in pressure or touch.
Alternatively, since the establishment of ommatidial polarity requires the coordination of two events (fate and direction of rotation) to create a single, wild-type outcome, suppression may require simultaneous mutations in more than one relevant pathway.
Transforming a single molecule to an active state may require simultaneous binding by multiple input signal molecules.
Suspecting that optimal array formation may require simultaneous production of receptors, CheA, CheW, some investigators have tried co-overexpression.
Thus, while the present dissociation method is not ideal for GFAP+ astrocyte recovery, more efficient and universal astrocyte identification may require simultaneous staining with multiple astrocyte markers (e.g. GFAP, GLT-1, ALDH1L1), regardless of dissociation method.
For example, play may require simultaneous performance of executive tasks (decision making, dual tasking), visual attention tasks (multiple object tracking, distractor rejection), visuomotor tasks (e.g. navigating), and rapid object recognition.
Similar(54)
The United Nations also agrees that the United States, as a condition to giving its consent to any such disposition or encumbrance, may require the simultaneous repayment of the balance of all installments remaining unpaid hereunder.
It is concluded that ATP can induce a form of synaptic facilitation which resembles only partially that induced by electrical stimulation and which may require the simultaneous activation of P1 and P2 receptors.
This suggests that most strategies of biological survival and adaptation to various lifestyles may require many simultaneous changes at molecular and cellular levels, rather than facile gain and loss of discrete groups of genes.
However, if in subsequent experiments these results extrapolate to mammalian brain, it would suggest that a therapeutic strategy to decrease tau hyperphosphorylation in AD and other tauopathies may require the simultaneous modulation of several phosphorylation sites.
As TRAIL alone failed to promote apoptosis, this Bim activation step is likely not sufficient, and efficient induction of cell death may require the simultaneous activation of different BH3-only molecules.
Related(20)
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