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New techniques as next generation sequencing may overcome issues on throughput time and cost, standard operation procedures and array design for individual crops.
In many cases, increased taxon sampling may overcome issues arising due to long-branch attraction, and we have collected a comprehensive data set of recA/RAD51 proteins in this study.
Further study of combination therapies (e.g., involving conventional cytotoxic agents, or targeted agents such as mTOR inhibitors, administered in combination with p53 modulators) is also needed as these may overcome issues pertaining to toxicity and efficacy of p53 modulator monotherapy.
The codetection of two mutations was also observed in circulating DNA samples therefore ddPCR mutation detection in free circulating DNA may overcome issues of tumor heterogeneity and detect rare mutations which might not be identified by studying a single site of disease.
Walsh and Jarvis [ 55] have pointed out that any epidemiological study using ISS to select patients with more severe injury may overcome issues related to 'selection bias' (i.e. factors apart from the injury itself influencing health care use such are hospital policies, bed supply, SES of the patient) that applies both to hospital admissions and A&E attendances.
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Thus, the rationale for introducing agents with a different mode of action may be to overcome issues related to class, particularly in cases of primary failure or recurrence of class-associated adverse events.
Time series data from the medium resolution sensor Landsat may overcome these issues.
Employing pluripotent stem cells, with an emphasis on directed differentiation, may overcome many issues currently associated with primary fat cell cultures.
Plasticized starch blends and composites and/or chemical modifications may overcome these issues, creating biodegradable polymers with sufficient mechanical strength, flexibility, and water barrier properties for commercial packaging and consumer products (Maurizio et al. 2005).
Novel platforms combining controlled release, improved adhesion, tissue penetration, and selective intestinal targeting may overcome these issues and potentially diminish the toxicity and high frequency of administration associated with conventional oral delivery.
Here, the fusion of human antibodies with a human RNase may overcome these issues.
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