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'may create issues' is a correct and usable phrase in written English.
You can use it when referring to a potential problem or conflict that could arise in a certain situation. For example, "This proposed plan may create issues with our current employees as it affects their workload."
Exact(6)
"It may create issues of status and power in the marriage".
"This always leads to misunderstanding between team members or sometime may create issues.
Major Hasan's decision to proceed on his own may create issues as the trial unfolds or if he is convicted.
If both the variables were continuous, we would have ended up having a quadratic problem, which may create issues with convexity if the quadratic terms appear in constraints.
However, the necessary calculations are too complex to perform with anything other than a scientific calculator or dedicated software, which may create issues in a clinical setting where access to electronic devices may be limited.
However, this may create issues for adoption in routine practice as more sessions would be more resource intensive (Schofield et al, in press) and patients may not be prepared to attend many more sessions, particularly because fatigue was a major problem (Aranda et al, 2005).
Similar(53)
The outcome of the US election may create new issues for Twitter with questions over fake news being shared and over far right posters using the service for abuse.
But, in the view of one of the world's leading economists, who is also a former top policy maker, the fiscal straitjacket constructed by European leaders to avoid the need for a rerun of the Greek problems in other countries may create fresh issues in the euro zone.
Not only are the cases of Afweyne and El Chapo more complicated than the simplistic tales of morality, stupidity, and hubris that we might want them to be, their apprehension while exploring movie projects may create thorny issues for future media and criminal investigations.
Additionally, due to the lack of a partner it cannot be applied in many cases of fertility preservation with medical or social indications, and may create controversial issues in case of divorce or separation of partners.
Corrective surgery after the initial operation may cost more and may create an issue of cost to fix a problem like epithelial ingrowth.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com