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This review will describe the molecular structure, cellular signaling pathways and current evidence for inflammasome activation following cerebral ischemia, and the potential for future treatments for stroke that may involve targeting inflammasome formation or its products in the ischemic brain.
It is anticipated that future therapy for breast cancer may involve targeting various HER receptors, their ligands [37] as well as metalloproteinases that mediate the cleavage of the ligands [43].
Such methods may involve targeting key phytoplasma-specific genes, or genes involved in pathogenicity using microRNAs.
Intervention may involve targeting the LSC self-renewal pathways or promoting their differentiation.
An optimal approach to countering progression of OA may involve targeting the cells of both bone and cartilage.
For surgical trials, this may involve targeting the limited resources available to research teams who have the resources and infrastructure to deliver larger multicentre trials.
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Future work may involve targeted overexpression of R2R3 MYB gene in various cotyledon, seed coat and other tissues in soybean.
Nec-1 was recently found to inhibit two other kinases, indicating that Nec-1-mediated protection may involve targets other than RIPK1 activity.
An important functionality of the GM-CSF domain may simply involve targeting of the vaccine to dendritic cells to promote more efficient presentation of the antigenic domain.
To clarify this issue, we added a sentence to the Results section stating: "Given that many direct miRNA targets are upregulated at the protein, but not transcript level, we expected that sequencing analysis of this stage would identify pathways that are dysregulated in the miR-1 knockout, some of which may involve direct miR-1 targets".
Given that many direct miRNA targets are upregulated at the protein, but not transcript level, we expected that sequencing analysis of this stage would identify pathways that are dysregulated in the miR-1 knockout, some of which may involve direct miR-1 targets.
Related(18)
may involve relating
may include targeting
may involve catering
may involve measures
may involve working
may enable targeting
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may favor targeting
may need targeting
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may highlight targeting
may necessitate targeting
may begin targeting
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