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In addition, the neuroprotective effect of α2-adrenoceptor agonists in the retina may involve stimulation of bFGF production.

The mechanisms of increased vascular permeability by VEGF may involve stimulation of collagenase production and proteolytic disruption of the endothelial basement membrane [ 6, 43].

Some peptides may even have potential against diseases of unknown aetiology (emerging infectious diseases), as their spectrum of activity is often very broad and may involve stimulation of the immune response of the host rather than targeting the pathogen.

The pro-apoptotic Bax protein is one of the major players in the mitochondrion form of apoptosis [ 26], and mitochondria-mediated cell death induced by resveratrol may involve stimulation of the expression of the bax gene by p53 or other transcription factors [ 10, 14, 27, 28].

Our previous clinical research showed that "Shenyang", a traditional Chinese medicine prescription made mainly from Radix codonopsitis, Radix astragali, Salvia miltiorrhiza and Glossy privet fruit, increases the post-operative survival rate of patients with oral SCCs and the mechanism of action may involve stimulation of the patient's immune function [ 7].

Similar(54)

The mechanisms underlying these effects remain unknown but may involve a stimulation of gluconeogenesis and increased glycogen stores, or may be related to hepatic lipotoxicity.

The associations of PCB and methylmercury exposures with indicators of allergy and allergic disease may involve both stimulation and inhibition of immune system functions.

The results of this study show that the antihypertensive effects of the crude methanol leaf extract of T. violacea in male SHR may involve the stimulation of muscarinic receptors, and reduction in plasma aldosterone levels.

In summary, the study presented herein demonstrates that RNASET2 protein overexpression is associated with vitiligo and that the underlying pathogenic mechanism may involve RNASET2 stimulation of cell apoptosis and hypersensitization to stress via the TRAF2 caspase pathway.

The mechanism by which prostaglandin analogs might cause anterior uveitis may involve the downstream stimulation of proinflammatory eicosanoids [123].

This stimulation may involve both TLR as well as non-TLR signaling systems in addition to the Fc receptor.

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