In addition, activation of central nervous system structures by stimulation of thickly myelinated sensory fibers in the auricular branch of the vagus nerve may require different stimulation patterns than the cervical branch, which is a mixed nerve with myelinated and non-myelinated efferent as well as afferent fibers.
There is no required delay in cancer treatment as this process would occur after cancer treatment is completed, however, similar to IVF, the recipient of the ova may require hormonal stimulation (to prepare the endometrium for embryo transfer) and subsequent increased estradiol levels.
While it is possible that IL-10 may have a direct repressive effect on pri-miR-155 transcription, a 2nd explanation could be that prolonged pri-miR-155 expression may require re-stimulation of the macrophages by pro-inflammatory cytokines in an autocrine manner.
Alternatively, an optimal response ex vivo may require re-stimulation with a major histocompatibility complex-presented antigen by using infected cells instead of an inert split antigen.
The results indicate that keratocytes do upregulate IL-1 β gene expression upon LPS stimulation but may require further stimulants for translation and secretion or may require a longer time frame.
Thromboxane in isolation may act mainly as a vasoconstrictor but may require other concurrent stimulation to act as a mitogen.
Therefore, the levels of IL-1β/IL-18-induced IκBζ protein may either not be sufficient for significant IFNγ production (in the absence of TNFα stimulation), or may require an additional TNFα-induced factor for activation of the IFNγ promoter.
However, neural tissue of different types and morphologies may require different wavelengths for optimal stimulation such that the optical penetration depth is matched to the targeted excitable tissue.
Furthermore, in vitro enumeration of progenitor cells for a quantity sufficient for a therapeutic treatment is associated with changes in phenotype and differentiation and risk of cell senescence and it may require artificial cell preactivation or stimulation.
Wavelengths of ∼1.87 and 2.12 μm, which exhibit similar absorption characteristics, have been extensively used across different applications, but other types of tissue may require different wavelengths for optimal stimulation such that the optical penetration depth is matched to the targeted excitable tissue.
