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Exact(5)

Therefore, we hypothesize that targeted inhibition of VEEV RdRp using artificial microRNAs may efficiently inhibit VEEV replication.

AMPK may efficiently inhibit the mammalian target of rapamycin kinase (mTOR; EC. 2.7.11.1).

Here, I hypothesize that manipulation of intracellular glutathione concentrations as protecting the cells form oxidative stress may efficiently inhibit tumor growth.

Thus, highly concentrated tryptic hydrolysate of rBLG may efficiently inhibit DPP-IV activity.

Strategies based on the application of certain antioxidants to prevent the accumulation of ROS and, consequently, the formation of mycotoxins may efficiently inhibit the production of certain mycotoxins but, concomitantly, may also induce the formation of other unwanted secondary metabolites.

Similar(55)

A putative functional role of this gene as an endosome efflux pump that sequesters iron and, possibly, other divalent cations from the endosomal system in macrophages [20], [21] suggested that lung macrophages from B6 mice may less efficiently inhibit M. avium growth compared to I/St-Nramp1r macrophages.

The therapeutic use of agents able to inhibit both EGFR and VEGFR may help to efficiently inhibit the activation of bypass pathways and overcome EGFR inhibitor resistance.

It could be envisaged that high levels of CCL3 may be needed to efficiently inhibit R5broad viruses and, as a consequence, to prevent MTCT of HIV-1.

This requirement for high molecular weight compounds to efficiently inhibit TryR may be a direct consequence of TryR possessing a large, solvent-exposed active site.

Together, our results demonstrated that the anti-mesothelin CAR-T cells efficiently inhibit the growth of pancreatic cancer PDX and may be a potential novel treatment strategy for patients with pancreatic cancer.

Thus, one can envisage that use of lhRNAs designed to efficiently inhibit at least two independent siRNA-susceptible regions may help to delay the onset of HIV-1 escape variants, especially when targeting only conserved sequences [46].

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