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Exact(6)
Several mechanisms are highlighted, including those that may disrupt thyroid activity, retinoid pathways, and sexual differentiation.
Animal and human studies suggest that BPA may disrupt thyroid function.
Animal and human studies suggest that PBDEs may disrupt thyroid function.
Hydroxylated polybrominated diphenyl ethers (HO-PBDEs) may disrupt thyroid hormone status because of their structural similarity to thyroid hormone.
Endocrine disrupting chemicals (EDCs) present in the environment may disrupt thyroid hormones, which in early life are essential for brain development.
Extrapolation of these findings in combination with the epidemiological MEHP evidence suggests that TBMEHP may disrupt thyroid function in humans in a manner similar to that of its unbrominated analog, MEHP.
Similar(54)
Other environmental pollutants, such as pesticides and mercury, may also disrupt thyroid function (Beard and Rawlings 1999; Ellingsen et al. 2000; Rathore et al. 2002; Watanabe et al. 1999).
Given the potential association between PFASs and thyroid hormones, concern arises about whether PFAS exposure may disrupt maternal thyroid hormone homeostasis during pregnancy.
Moreover, the chemicals may disrupt human thyroid hormone functioning and cause other health effects, prompting many nations to ban or suspend their use in new consumer goods.
Certain PCB congeners, notably those that disrupt thyroid hormone, may inhibit or alter thyroid hormone-regulated gene expression and push brain development toward an autistic phenotype (56, 57).
Moreover, the simultaneous exposure to other breast milk contaminants (e.g., polychlorinated biphenyls, polybrominated diphenyl ethers, dioxins) that can disrupt thyroid function by other modes of action may interact with perchlorate in infants.
Related(18)
may destroy thyroid
may encourage thyroid
may require thyroid
may depress thyroid
may suggest thyroid
may screen thyroid
may impact thyroid
may decrease thyroid
may have thyroid
may experience thyroid
may impair thyroid
may influence thyroid
may alter thyroid
may disturb thyroid
may occur thyroid
may affect thyroid
may cause thyroid
may trigger thyroid
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