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In the absence of any other factors that may impair thyroid reserve, including smoking, iodine depletion and subclinical autoimmune thyroiditis, the demonstrated and diminished thyroid reserve can be attributed to TW infection.
Background: Animal studies suggest that some perfluoroalkyl acids (PFAAs), including perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA) may impair thyroid function.
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Impaired thyroid gland function, goitre, and other adverse effects may result from high intakes of iodine from food, iodized salt, or pharmaceutical preparations intended to prevent or treat iodine deficiency or other disorders.
Our result suggested that the two test chemicals could impair thyroid hormone action by suppressing its transcriptional activity.
Numerous studies have now shown PFAAs to impair thyroid hormone homeostasis in animal studies.
Individuals who were on medications that could potentially impair thyroid function e.g. Lithium were excluded.
Researchers have found that it may impair the functioning of the thyroid, potentially stunting the growth of fetuses, infants and children.
A disturbance of the thyroid hormone homeostasis may impair the reverse cholesterol transport process, which in turn may result in a decrease of HDL, a characteristic of subclinical hypothyroidism [ 36].
A detailed study now provides one of the most insightful assessments to date of how environmentally relevant levels of PBDEs may impair brain development by interfering with thyroid hormone receptor (TR)–mediated transcription [ EHP 119(2):168–175; Ibhazehiebo et al.].
Tranquillisers: These drugs may impair driver reaction times and can cause drowsiness.
Both are costly and anxiety-provoking and can also have complications that may impair fertility.
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