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Iterative searching with HMM profiles was also used to identify other proteins that may contain putative SLIDE domains.

Allelic imbalance or loss of heterozygosity (LOH) studies have been used extensively to identify regions on chromosomes that may contain putative tumour-suppressor genes.

We hypothesized that these areas may contain putative oncogenes or tumor suppressors, as in the case of the TET2 tumor suppressor.

Comparative genomics analysis against fully-sequenced soil bacteria P. JDR2 and P. vortex showed that regions of poor conservation may contain putative virulence factors.

As a result of the redundancy within the 'seed' region, predictive algorithms have suggested that up to a third of all genes may contain putative single or multiple MREs and might therefore be regulated by changes in miRNA expression [ 22].

Similar(55)

Although experimental studies have detected the presence of large transcripts in M. hyopneumoniae, which could be transcribed from the promoter upstream of the first CDS of the transcriptional unit, our study demonstrates that many internal CDSs may also contain putative promoters.

In conclusion, as summarized in Figure 9, acute TNF-α stimulation of Calu-3 cells leads to increased eicosanoid and IL-8 release, the latter relying on the integrity of DRM, which may contain a putative CFTR/cPLA2α/ANXA1/p11 complex.

Maize may contain two putative paralogs of ZmTTK1 (GRMZM2G088409; GRMZM2G068192) with highly conserved kinase domains (63 and 65% identity), but reduced homology in the N-terminal domains (34% and 36% identity, respectively).

Recently, however, it was suggested that IL-17 receptors may contain a putative TIR (Toll/IL-1 receptor) domain in the intracellular region [ 7], and the IL-17R tail also contains at least two putative TNF receptor-associated factor (TRAF -binding domains (Gaffen SL, unpublished observaTRAF -binding

We initially investigated for the presence of sphere-forming cells in the H28, H2052 and Meso4 MPM cell lines as tumour spheroids are believed to contain putative CSCs which may play a crucial role in chemoresistance [ 12, 15, 17- 19].

Considering that all these sequences contain putative signal peptides – identified by SignalP 3.0 [ 46] – and their relative abundance, we suggest that these ESTs may encode secreted venom components.

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