Sentence examples for may confer disease from inspiring English sources

Furthermore, we examined the expression of ERBB3 in human islets, the effect of ERBB3 knockdown on apoptosis in insulin-producing INS-1E cells and the genetic and regulatory architecture of the ERBB3 locus to provide insights to how rs2292239 may confer disease susceptibility.

Whether sequence variation may confer disease susceptibility is also not known.

Emerging evidence suggests that vaccination against virulence factors of these pathogens and anti-inflammatory therapy may confer disease resistance.

Based on the findings in the present study and the previous reports [ 16, 17], we conclude that the heterozygous genotypes of SNPs rs281432(C/G) and rs5498 E469K(A/G) in the ICAM-1 gene may confer disease risk.

13 There are some indications that memantine may have mechanisms of action which may potentially confer disease-modifying effects, 4 but this has not been established in clinical studies.

According to the ancestral-susceptibility model, some mtDNA haplogroups may confer certain disease susceptibility, as well as the penetrance of the clinical phenotype, with the change of environment and lifestyle in modern time (Wallace, 2005).

Varying individual responses to the levels and effects of the metabolic products of adiposity, the adipocytokines, may confer differing disease risks.

Since its alleles vary among individuals and may confer variable disease susceptibility, analyses of MICA alleles maybe useful in cancer investigation.

TMEM106B genetic variants may confer increased disease risk by increasing levels of TMEM106B expression, since mRNA expression levels of TMEM106B are >2.5-fold higher in FTLD-TDP cases vs. controls [ 18], and are particularly increased in FTLD-TDP cases with GRN mutations [ 24].

Specifically, we predict that the population severely impacted by disease would experience directional or balancing selection at immunologically important genes, as genetic variation at these loci may confer resistance to disease (Schröder and Schumann 2005; Froeschke and Sommer 2005; Barreiro et al. 2009, Savage and Zamudio 2011; de Assunção-Franco et al. 2012).

Malaria is caused by the hematoprotozoan of the genus Plasmodium and provides one of the best examples of how positive selective pressure upon host genetic variants may confer resistance to disease.