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Exact(11)
Virus-induced unfolded protein response (UPR) may activate autophagy to support the virus life cycle.
Therefore, HIF-1 α may activate autophagy through the nonselective system.
Therefore, p62 reduction, similarly to MTORC1 inactivation, may activate autophagy [ 72].
Tumor cells may activate autophagy in response to cellular stress and increased metabolic demands related to rapid cell proliferation.
JNK-mediated protection from oxidative stress is abolished in flies with compromised autophagy, and the induction of JNK signaling may activate autophagy through FOXO [ 198].
This causes a burden on the ER that may activate autophagy and the UPR response, which may lead to pancreatic cell death.
Similar(49)
Thus, upregulation of Beclin 1 may drive not only host protection in the CNS but may also activate autophagy as a homeostatic mechanism to reduce cellular damage.
Cells exposed to ER-stress undergo the Unfolded Protein Response (UPR) to avoid apoptosis, but may also activate autophagy.
Axotomy and ONT destroy the integrity of RGC axons, and oxidative stress may initially activate autophagy in axons to avoid axonal degeneration and neuron cell death.
The temporal sequence of these processes in the tumor microenvironment remains unclear, but our current work shows that activation of the central player of ecophagy, POX, may precede and activate autophagy.
So inhibition of Akt may activate some autophagy-related proteins and induce autophagy.
Related(20)
may trigger autophagy
may promote autophagy
may affect autophagy
may be autophagy
may keep autophagy
may induce autophagy
may activate estrogen
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may cause autophagy
may activate p53
may block autophagy
may impair autophagy
may increase autophagy
may activate pigment
may undergo autophagy
may control autophagy
may activate hypertrophy
may limit autophagy
may target autophagy
may benefit autophagy
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