Sentence examples for maximum lifespan extension from inspiring English sources

This is in disagreement with experiments testing the effect of a range of bacterial concentrations on worm lifespan using a plate-assay, where no food caused the maximum lifespan extension [37].

Interestingly, the effects of metformin are most pronounced in mid-life without maximum lifespan extension, indicating that at this concentration, metformin treatment specifically impacts median lifespan of the culture.

DAF-16 function is controlled by additional mechanisms beyond its nuclear localization, as neither constitutive nuclear localization nor over-expression is sufficient to induce maximum lifespan extension [ 16].

Genetic interventions resulting in pituitary dwarfism in mice, which causes growth factor reduction (GFR) and a reduction in associated signaling, also result in maximum lifespan extension [ 8], with a concomitant reduction in cancer severity [ 9, 10].

Remarkably, although initially with adverse effects in males, flies expressing RNAi specific for AcCoAS exhibited mean and maximum lifespan extension in both sexes compared to isogenic control flies that expressed an unrelated RNAi specific for GFP not present in this organism.

In humans, where advances in health care have led to longer median, but not maximum, lifespans, this extension of healthspan is termed "compression of morbidity" or "healthy aging".

We refer to the first local maximum on the lifespan extension curve as DR. This occurred at 5 × 10 C.F.U.

This increase in healthspan occurs without a concomitant extension in maximum lifespan.

This effect will preclude extension of maximum lifespan, even if the aging is slowed in remaining alive (but faster aging) mice.

In these flies, no differences in survival were observed until after the flies were aged 50 days, after which experimental flies consistently out-lived controls, resulting in a significant extension of their maximum lifespan.

The dilp2RNAi/d2GAL genotypes both displayed a small extension of median, but not maximum, lifespan in two out of three starvation trials (Figure 3).