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Main Outcome Measures: Lung volume, peak expiratory flow (PEF), MIP, and maximum expiratory pressure (MEP) were measured by using a spirometry and inspiratory force meter, respectively.
Intervention: The training group (part 2) performed three series of 15 contractions against an expiratory resistance (60% maximum expiratory pressure [PEmax]) two times a day, whereas the control group performed breathing exercises to enhance maximal inspirations.
Dependent variables included maximum expiratory pressure (MEP), Voice Handicap Index (VHI) score, Vocal Rating Scale (VRS) score, Voice Effort Scale score, phonetogram measures, subglottal pressures, and acoustic and perceptual measures.
Higher AGFRs were found to result in larger increase in maximum expiratory pressure.
SGRQ improved equally in both groups and the singing group had an improvement in maximum expiratory pressure.
FVC Forced Vital Capacity, FEV 1 Forced Expiratory Volume in the first second of forceful exhalation, PImax Maximum Inspiratory Pressure, PEmax Maximum Expiratory Pressure.
Similar(47)
ALS: Amyotrophic lateral sclerosis; NIV: Non-invasive ventilation; FVC: Forced vital capacity; FEV 1: Forced expiratory volume exhaled in 1s; PCF: Peak cough flow; MIP: Maximum inspiratory mouth pressure; MEP: Maximum expiratory mouth pressure; SNP: Sniff nasal pressure.
ALS: Amyotrophic lateral sclerosis; NIV: Non-invasive ventilation; FVC: Forced vital capacity; PCF: Peak cough flow; MIP: Maximum inspiratory mouth pressure; MEP: Maximum expiratory mouth pressure; SNP: Sniff nasal pressure; PEG: Percutaneous endoscopic gastrostomy.
Additional measurements included dyspnoea at rest, forced vital capacity (FVC), peak cough flow (PCF), maximum inspiratory mouth pressure (MIP), maximum expiratory mouth pressure (MEP), and sniff nasal pressure (SNP); all of which are considered secondary criteria for NIV diagnosis.
Respiratory muscle tests included assessments of peak cough flow (PCF), maximum inspiratory mouth pressure (MIP), maximum expiratory mouth pressure (MEP), and sniff nasal pressure (SNP), all measured with MicroRPM® (Cardinal Health, Chatham, UK).
BMI = body mass index, ERT = enzyme replacement therapy, FVC = forced vital capacity, FEV1 = forced expiratory volume in one second, MIP = maximum static inspiratory pressure, MEP = maximum static expiratory pressure.
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