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The platelet component was calculated as MCEEXTEM - MCEFIBTEM, where maximum clot elasticity MCE = (MCF*100)/(100-MCF) [ 23].

For all ROTEM® parameters, the ROC-AUC remained unchanged if clot elasticity was used instead of clot firmness (for example, maximum clot elasticity (MCE) instead of MCF).

We will therefore continue to use the term CE within this article, in relation to the parameters G, E, EMX, CE, and maximum clot elasticity (MCE).

The sensitivity of this approach may be increased by using the maximum clot elasticity (MCE; Table  1) rather than MCF to measure clot quality.

The platelet component of clot elasticity was calculated from EXTEM and FIBTEM maximum clot elasticity values (EXTEM MCE FIBTEM MCE), which were derived from MCF measurements as described previously.

CFT: Clot formation time; CT: Clotting time; CBC: Complete blood count; CI: Confidential interval; MCE: Maximum clot elasticity; MCF: Maximum clot firmness; ROC: Receiver operating characteristic; Se: Sensibility; Sp: Specificity; TEG: Thromboelastography; TEM: Thromboelastometry All authors declare that they have no competing interests.

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Similar(53)

The clot formation time (CFT) and maximum clot firmness (MCF), but not clotting time (CT), were strongly correlated with the fibrinogen level and platelet count.

Haemodilution with albumin significantly attenuated EXTEM maximum clot firmness (MCF), α angle (AA), clotting time (CT) and clot formation time (CFT), and FIBTEM MCF (P <0.001).

Clotting time (CT), clot-formation time (CFT), maximum clot firmness (MCF), alpha angle, and the 60-minute lysis index were determined.

HF diagnosis was established when the 60 minute clot lysis index (CLI60) was below 85% of the maximum clot firmness.

Using different activators for extrinsic and intrinsic activation and heparin inactivation by heparinase, the onset of coagulation (coagulation time), kinetics of clot formation (clot formation time), and maximum clot firmness were measured.

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