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The authors indicated that in all four tests - extrinsic thrombelastometry, intrinsic thrombelastometry, fibrinogen thrombelastometry, and aprotinin thrombelastometry - the clot formation time was significantly shorter and maximum clot formation was significant higher compared with healthy controls, indicating a risk for thrombosis.
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Hypothermia lengthened the following: ExTEM clotting time (CT), clot formation time and α angle; FibTEM maximal clot formation (MCF).
EXTEM maximum clot firmness (MCF), clot formation time (CFT) and α angle (AA) decreased significantly upon dilution with all colloid solutions (P <0.001), although a significantly greater coagulopathic effect was seen for samples diluted with synthetic colloid solutions versus albumin (P ≤0.001).
Recently, two additional TEG parameters – maximum velocity of clot formation (MaxVel) and time to reach MaxVel (tMaxVel) -were reported for both versions of the TEG instrument [ 77, 88].
Correlation between recorded data standard ROTEM parameters and derived thrombodynamic ROTEM parameters (potential index (TPI), maximum velocity of clot formation (MaxV), time to MaxV (MaxVt), AUC) were analyzed using SPSS 19.0.
The clot lysis time was defined as the time from the midpoint of the clear to maximum turbid transition, representing clot formation, to the midpoint of the maximum turbid to clear transition, representing the lysis of the clot.
The ROTEM® analysis displayed significantly an amplified maximum clot firmness (MCF), a shortened clot formation time (CFT) und an increased α-angle.
Clotting time (R), velocity of clot formation (alpha angle), and maximum strength of the clot (maximum amplitude, MA) were recorded using a 5000 series TEG analyser (Haemoscope Corporation, Niles, IL, USA).
Clotting time (CT), clot-formation time (CFT), maximum clot firmness (MCF), alpha angle, and the 60-minute lysis index were determined.
Thromboelastogram demonstrated an improvement in the time to onset of clotting, the rate of clot formation, the maximum amplitude, the time to reach stable clot, and the rate of subsequent clot lysis [ 18].
In the observational cohort study, blood samples were obtained from patients on the day of diagnosis of severe sepsis (n = 56) and from postoperative patients (n = 52), and clotting time, clot formation time, maximum clot firmness, alpha angle, and lysis index were measured with thromboelastometry.
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