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The overarching goal for most of these biomaterials is its ability to closely mimic native extracellular matrix of tissues.
In this chapter, we intend to describe the development of electrofluidodynamic technique as a set of processes that allow obtaining a variety of hierarchical architectures based on electrospun fibers that mimic the native extracellular matrix of tissues.
However, IGFBP5 also binds to the extracellular matrix of tissues, and can thereby serve as a local reservoir of IGF-1 [ 23].
Perlecan may also occur outside the basement membranes, that is, in the extracellular matrix of tissues deprived of these structures, as in the case of the matrix of cartilage, sinusoid vessels of liver, spleen, or in the lymph nodes [ 35].
Fibronectins (FNs), a family of multifunctional adhesion proteins that differ from one another through alternative splicing of a pre-mRNA derived from a single gene, are found as soluble dimeric molecules in the blood and as insoluble multimers within the extracellular matrix of tissues, where they are concentrated in basement membranes and blood vessel walls [ 1- 3].
Similar(55)
This is due to the limited fragmentation efficiency of singly charged ions, which are produced in MALDI almost exclusively, and to ion suppression effects in the complex matrix of tissue sections.
Hydrogels derived from natural polysaccharides are ideal scaffolds as they resemble the extracellular matrices of tissues comprised of various glycosaminoglycans (GAGs).
The extracellular matrix (ECM) of tissues is an assembly of insoluble macromolecules that specifically interact with soluble bioactive molecules and regulate their distribution and availability to cells.
Collagen is an abundant protein found in the extracellular matrix of many tissues.
The topography of the electrospun nanofibrous scaffolds resembles that of the natural extracellular matrix of human tissues.
Biglycan (bgn) is a small leucine-rich proteoglycan (SLRP) enriched in the extracellular matrix of skeletal tissues.
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