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The study was approved by the Ethics and Scientific Committees of the University General Hospital of Heraklion and all patients gave their written informed consent for the use of the tissue material for translational research.

Basic research provides raw material for translational advances.

There is a vital need for well-characterized patient material for translational research [ 13].

The study was approved by the institutional ethics committee and all patients gave the informed consent for the use of the tissue material for translational research.

The study has been approved by the institutional ethics committee and all patients gave their informed consent for the use of the tissue material for translational research.

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In addition, patients who were willing to provide biological material for future translational research studies signed a separate informed consent.

Thus, in contrast to other models, such as MMTV-PyMT and MMTV-wnt1, in which pooling individual mouse tumors can generate sufficient material for basic and translational studies [ 16, 42], Brca1 tumors will need to be analyzed individually and these studies are limited by the size of each original tumor.

Given the complex nature of clinical tumor biobank material that forms the basis for translational cancer research, the development of bioinformatic tools that can process data from heterogeneous tumor samples with varying fractions of normal cells is of great importance.

Produced under optimal conditions of standardization and safety, human platelet materials can become the future 'gold standard' supplement for ex vivo production of MSCs for translational medicine and cell therapy applications.

We offer our conceptual framework for translational health disparities research and our framework for translational health education research as guiding principles to improve our translational efforts.

The mean AA outline is linear for translational motions.

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