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Furthermore, bisulfite sequencing across matched tissues from human and mouse revealed strongly conserved patterns of DNA methylation in CpG island regions of SHANK3 promoter regions (including alternative promoters) [11].

The analysis of TWIST1 expression levels in tumor and normal matched tissues from 151 patients with colorectal cancer showed that the expression of TWIST1 is restricted to the tumor mass.

In contrast to the brain, the levels of hASM in the mouse spinal cord were not significantly above background (noted in matched tissues from aCSF-infused mice) in the majority of animals analyzed (Figure 4b).

Our global data extend these studies, exploring CTCF-binding evolution in matched tissues from six mammals.

The expression of sPLA2-IID, sPLA2-III, sPLA2-V and COX-2 proteins was analysed in tumours and normal matched tissues from three to four patients.

miR-124 expression was decreased significantly in CRC tissues compared to the adjacent normal colonic tissues in a panel of matchedtissuesfrom  17  CRC  patients.

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Similar(53)

Interpretation of these data is made more difficult by the lack of matched tissue from healthy control subjects.

All the scFvs tested strongly stained tumor cells and were negative with normal matched tissue from patient B93 (Fig. 6).

For 14 of 31 relapsed cases, tissue from the metastasis was available and was analysed in parallel with matched tissue from the primary cancer for CEBPδ expression.

No background hybridization was seen when replicate tissue sections were incubated with an unrelated digoxigenin-labeled probe with similar guanine-cytosine content or when matched tissue from unaffected dogs were incubated with the DogCV-specific probe (23 – 23 ).

As shown in Figure  5C, using matched tissue from these patients, we observed no difference in the mean ALDH1 score from tumor tissue obtained at biopsy versus tissue obtained at surgical resection (biopsy mean ALDH1 score 46 ± 34 vs. resection mean score 44 ± 27, P = 0.86).

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