massively parallel sequencing

USAGE SUMMARY

The phrase "massively parallel sequencing" is correct and usable in written English.
It can be used in the context of discussing advanced DNA sequencing technologies that allow for the simultaneous processing of multiple sequences. Example: "Massively parallel sequencing has revolutionized genomics by enabling researchers to sequence entire genomes quickly and affordably."

✓ Grammatically correct

Science

Human-verified examples from authoritative sources

Exact Expressions

60 human-written examples

We have recently introduced massively parallel sequencing for mutation detection in clinical cancer specimens [20].

Plosone

Furthermore, massively parallel sequencing robustly and accurately identified all mutations present in the dataset.

Plosone

TGE: Targeted genomic enrichment; MPS: Massively parallel sequencing.

BMC Genomics

These mutations were mainly detected with TaqMan assays, massively parallel sequencing approaches and mathematical modelling.

BMC Cancer

Shotgun fragment libraries were hybridized to custom microarrays, and then enriched using massively parallel sequencing [ 8].

BMC Medical Genomics

Massively parallel sequencing technology allowed us to accurately detect miRNAs expressed in B-cells.

BMC Genomics

Ng, S. B. et al. Targeted capture and massively parallel sequencing of 12 human exomes.

Nature

Chiang, D. Y. et al. High-resolution mapping of copy-number alterations with massively parallel sequencing.

Nature

Chiang, D.Y. et al. High-resolution mapping of copy-number alterations with massively parallel sequencing.

Nature

Imielinski, M. et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Nature

Dahl, F. et al. Multigene amplification and massively parallel sequencing for cancer mutation discovery.

Nature

Expert writing Tips

Best practice

When writing about genomic research, use "massively parallel sequencing" to specifically highlight the high-throughput nature and scale of the sequencing method, differentiating it from older Sanger sequencing methods. This conveys the advanced capabilities of the technology.

Common error

Avoid using "massively parallel sequencing" interchangeably with Sanger sequencing. The former is a high-throughput method capable of sequencing millions of DNA fragments simultaneously, while Sanger sequencing is a first-generation, lower-throughput method.

Linguistic Context

The phrase "massively parallel sequencing" functions as a noun phrase, typically used as a subject or object in a sentence. Ludwig indicates it is grammatically correct and widely used, as evidenced by the numerous examples provided.

Expression frequency: Very common

Frequent in

Science

100%

Less common in

News & Media

0%

Formal & Business

0%

Academia

0%

Ludwig's WRAP-UP

"Massively parallel sequencing" is a widely used and grammatically correct term referring to advanced DNA sequencing technologies, according to Ludwig. Predominantly found in scientific contexts, this noun phrase describes high-throughput methods revolutionizing genomic research. While alternatives like "next-generation sequencing" and "high-throughput sequencing" exist, "massively parallel sequencing" specifically emphasizes the scale and parallel nature of the process. As Ludwig's examples show, this technology enables rapid gene discovery, accurate mutation detection, and comprehensive genomic analysis.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

Next-generation sequencing

Broader term encompassing various high-throughput sequencing technologies, including massively parallel sequencing.

High-throughput sequencing

Focuses on the high-throughput nature of the sequencing process.

Deep sequencing

Emphasizes the depth of coverage achieved in sequencing, often a result of massively parallel approaches.

Second-generation sequencing

Refers to a specific era of sequencing technologies that included massively parallel methods.

Multiplex sequencing

Highlights the ability to sequence multiple samples simultaneously.

NGS

Acronym for Next Generation Sequencing, which is a shortened version of the original term.

DNA sequencing

A more general term for reading a sequence of DNA. The term "massively parallel sequencing" specifies the sequencing methodology.

Whole-genome sequencing

This alternative refers to sequencing the entire genome, as opposed to targeted regions. The term "massively parallel sequencing" specifies the sequencing methodology.

RNA sequencing

Sequencing method used to analyze RNA molecules, often employing massively parallel methods.

Parallel DNA analysis

Describes the parallel processing of DNA samples for analysis.

FAQs

How does "massively parallel sequencing" differ from traditional Sanger sequencing?

"Massively parallel sequencing" allows for the simultaneous sequencing of millions of DNA fragments, greatly increasing speed and throughput compared to the traditional Sanger method. This makes it ideal for large-scale genomic studies.

What are some applications of "massively parallel sequencing" in research?

"Massively parallel sequencing" is used in various applications, including whole-genome sequencing, RNA sequencing, metagenomics, and targeted sequencing for identifying genetic variations.

What does NGS stand for, and how is it related to "massively parallel sequencing"?

NGS stands for Next-Generation Sequencing, and it's a broader term encompassing various high-throughput sequencing technologies, including "massively parallel sequencing".

Are there alternative terms to "massively parallel sequencing"?

Yes, you can use "high-throughput sequencing" or "next-generation sequencing" as alternative terms, depending on the specific context. The acronym NGS is also an acceptable alternative.