Sentence examples for marks of chromatin from inspiring English sources

5-Methylcytosine and methylated histones have been considered for a long time as stable epigenetic marks of chromatin involved in gene regulation.

A recent study has uncovered that, in several loci of Arabidopsis, Pol IVb's role as the effector of RNA silencing is independent of its function in siRNA biogenesis, and the study proposed that some epigenetic marks of chromatin adjacent to the Pol IVb-targeted region could influence the ability of Pol IVb-guided DNA methylation [62].

Histone post-translational modifications -PTMs- are marks of chromatin environments.

Specifically, various studies indicate that a number of key developmental and pluripotency genes are marked by bivalent marks of chromatin activation (H3K4me3) and repression (H3K27me3) that maintain genes in a "transcription-ready" state that allows rapid transcription activation upon differentiation of ESC [4], [5].

The epigenomic state of early embryos is set and largely governed by a group of genes (EMGs, as named previously) that play roles in reading, writing, and erasing the epigenetic marks of chromatin.

The differential marking of chromatin at Myog and CKm at this time point is remarkable because the Myog gene is already transcribed before adding DRB at 24 h of differentiation, whereas the CKm gene has not yet begun to be expressed at this stage of differentiation.

ESC are characterized by an unusual chromatin features where marks of open chromatin, such as acetylated H3K9 and trimethylated H3K4, are combined with repressive histone modifications like H3K27 trimethylation at some non-expressed genes [3], [4], [5], [6], [7].

Early S replicating sequences are assembled into nucleosomes enriched with acetylated histones H3 and H4, the marks of open chromatin, as opposed to late S replicating DNA, which is packaged mainly into silent chromatin marked by deacetylated forms of these same histones [ 107, 108].

Specific histone post-translational modifications are known marks of peculiar chromatin environments.

In mammalian cells, the majority of modifications detected on H3.3 are also marks of active chromatin, including methylation of K4 and K79 and acetylation of K14, K18, and K23 (Hake & Allis, 2006).

Interestingly, for non-genic regions, H3K9me3 still occupies different sequences from those associated with other histone marks, but H3K27me3-occupied non-genic sequencannotnnot be distinguished from those occupied by marks of active chromatin (Additional file 4: Figure S3B).