Sentence examples for marks in mouse from inspiring English sources

Acute inhibition of translation rapidly depletes euchromatic marks in mouse ESCs and blastocysts, concurrent with delocalization of RNA polymerase II and reduction in nascent transcription.

Pezic et al. (14) found that piRNAs target active LINE1s to establish repressive H3K9me3 marks in mouse spermatogonia.

Another study found that changes in histone methylation marks in mouse macrophage cells were only visible after 24 h of exposure when oxygen levels were below 3%.

Despite the presence of enhancer specific histone mark of H3K27ac, we could not find evidence of low-level antisense transcripts at the enhancer marks in mouse suggesting that enhancers at close range that do not generate e-RNAs may regulate the three genes in mouse.

By using the antibody we have developed against H3K14ac and another published commercial antibody against H3K9ac, we made genome-wide location analysis of these two acetylation marks in mouse (m) ES cells, and compared the presence of two marks over various genomic regions.

Since DNAse-I HSS usually coincide with the active promoter specific histone mark of trimethylated Histone 3 lysine 4 (H3K4me3) [ 39] and transcriptionally active enhancers may also bear the specific histone mark of acetylated Histone 3 lysine 27 (H3K27ac), we looked for these two marks in mouse cerebellum and mouse cortex.

Epigenetic marks in mice that mosaically reverse some but not other sexually dimorphic behaviors and gene expression profiles in the brain can and do carry over across generations and contribute to heritable discordance between the gonad and behavior 22– 22.

Summarizing, these data suggest that Ring1b is involved in direct regulation of RNAPII controlled promoters with 'high' CpG content and epigenetically distinct histone marks, namely bivalent marks or the active H3K4me3 mark, in mouse ES cells.

Here we showed that the Xi is coated by XIST RNA and displays the same specific combination of repressive histone marks as in mouse and human (Table 1).

Inhibition of tumor growth was most marked in mice treated with Ad.p35 plus Ad.p40 plus Ad.CD/5-FC (p < 0.001 for Ad.p35 plus Ad.p40 plus Ad.CD/5-FC Ad.CD/5-FCand p < 0.0053 for Ad.p35 plus Ad.p40 plus Ad.CD/5-FC vs Ad.GFP5-FC).

A parallel example of inheritance of epigenetic marks in the mouse is provided by the Axin-fused (Axin Fu) allele, which is involved in embryonic axis formation (Rakyan et al., 2003).