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A large number of new markers are emerging which aim to further delineate the basal phenotype [ 23, 25].
Attempts for high throughput discovery of SNP markers are emerging but only a limited number of true SNP have been validated up to now [ 22].
Finding the right marker to predict renal function in all of these situations may be impossible, but new markers are emerging that seem to perform better than serum creatinine alone.
It is fortunate that many genetic markers are emerging for AD and FTLD, and there is increasing knowledge about biomarkers that can potentially be tracked years before clinical symptoms emerge in EOFAD.
5, 6 Consequently, new markers are emerging, such as the count of circulating tumor cells (CTCs), defined by the US Food and Drug Administration FDAas as the number of EpCAM-positive epithelial nucleated cells >4 µm in diameter in a 7.5 mL blood sample.
Similar(55)
Associations between TNFα and other "downstream" inflammatory markers which are emerging risk predictors (fibrinogen, CRP, white cell count, plasma viscosity, vWF, Factor VIII, t-PA and D-dimer) were modestly positive, similar to other reports [11,24] and unlikely to result in collinearity.
Several protein markers of potential prognostic value are emerging, mainly tissue based, but increasingly in biological fluids such as serum and plasma.
Novel ER stress markers for drug responsiveness prediction are emerging as there has been an increasing recognition of an association between ER stress and human cancer, and an improved understanding of the diverse underlying molecular mechanisms [ 24].
New studies that aim to target both genetic and epigenetic alterations (noncoding microRNA) underlying malignant properties of tumor cells and to specifically attack tumor cells using cell surface markers overexpressed in tumor tissue are emerging.
Genetic markers of increased vulnerability to neurotrauma are emerging and numerous studies implicate apolipoprotein E4 as a major genetic risk factor associated with poor clinical outcome after TBI (reviewed in [ 79]-[ 83]).
Slowly, leaders are emerging.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com