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Exact(6)
CD38 is a marker of lymphocyte activation.
CD73, also known as ecto-5′-nucleotidase, is an enzyme used as a marker of lymphocyte differentiation [ 20].
Regrettably, the investigators did not measure programmed cell death-1 on T cells, which is a reliable marker of lymphocyte exhaustion in both mice and humans [ 1].
Presence of certain transcription factors is considered as a marker of lymphocyte subsets, and these factors can regulate themselves and one another creating positive or negative feedback loops and setting the differentiation conditions [ 13].
In patients with liver disease and without renal impairment or concomitant hematologic disorders, serum β2-MG represents a non-specific marker of lymphocyte activation and proliferation, resulting in a Th-1 mediated Th-1 mediatedse (Frenimmunel. 1997).
Alternatively, since CD69 is a nonspecific marker of lymphocyte activation, an immune response to another infectious agent would have elevated a participant's baseline CD69 level, making it difficult to determine whether their PBMCs were responding to coccidioidin or another infection or both.
Similar(54)
A good activation marker of lymphocytes is IFN‐γ.
The proportion of activated NK cells was assessed from the cells expressing CD69, an early activation marker of lymphocytes [ 18], within the CD56+CD3- NK cell fraction.
The signature of an adaptive response would entail cellular markers of lymphocyte maturation/activation (e.g., B and T cell receptors and co-receptors, activation-induced cytidine deaminase, antibodies), antigen presentation (e.g., LMP7, TAP1, cathepsines, MHC molecules) as well as cytokine production (e.g., IL-2, IL-4).
Markers of lymphocyte activation have also been shown to predict disease progression in HIV-infected patients.
The cytokines up-regulated in this study are markers of lymphocyte activation and mediators of inflammation [ 30- 32] and may play a role in the modification of the B lymphoblasts leading to cell death.
Related(20)
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