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selection marker of erythromycin resistant.
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An adult study using a higher oral dose of erythromycin (1 g/day), reported improvement in segmental and colon transit time assessed using radio-opaque markers [ 21].
The standard curve of erythromycin titer was obtained using erythromycin A standard sample (97% purity).
The high requirement of erythromycin market stimulates the research on the improvement of the production and productivity of erythromycin.
In the case of erythromycin, the E. coli K12 assay strain was engineered to produce an erythromycin inactivating esterase, PlpA.
It was found that the electrochemical behavior of erythromycin A differs from that of azithromycin dihydrate.
This led to the severe fluctuation of erythromycin production on industrial scale.
Success establishes E. coli as a viable option for the heterologous production of erythromycin A and more broadly as a platform for the directed production of erythromycin analogs.
There was over a twofold increase in erythromycin biosynthesis and the ratio of erythromycin A (EA) to erythromycin C (EC) increased from 2 1 to 6 1 (base only pH control) to 11 1 (full pH control).
Transformants were selected on GAM plates containing 1% d-glucose and 5 μg/mL of erythromycin.
Our results indicated that Rv3197 affected the susceptibility of erythromycin (Table S1).
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