Sentence examples for marker of dysfunctional from inspiring English sources

Measuring both markers simultaneously can be envisaged as an index that may play the role of a surrogate marker of dysfunctional HDL in inflammation and oxidative stress conditions.

Whether oxidized HDL-proteins by MPO activity are a good marker of dysfunctional HDL and CVD risk remain to be validated in large-scale studies.

It remains to be tested whether the identification of distorted cardiac JAIL may serve as marker of dysfunctional vascular endothelium and/or provide new targets for protective interventions.

Volume of infarct did not contribute to predicting error rate in either naming or comprehension, independently of volume of hypoperfusion, because in acute stroke the volume of hypoperfusion (when available) is a better marker of dysfunctional tissue than volume of infarct.

We have previously observed serine appearance in the media from all bovine oocytes with developmental potential (Hemmings et al., 2012) suggesting that serine depletion could be a marker of dysfunctional oocyte metabolism and hence poor oocyte quality recorded from women with PCO morphology.

Markers of dysfunctional autophagy have been described in motor neuron disease spinal cord (Otomo et al., 2012), and the autophagy lysosome system plays a role in degrading superoxide dismutase 1 and TBP43 (now known as TARDBP) (Otomo et al., 2012).

PD-1 has been identified as a marker for dysfunctional T cells, and blockade of PD-1 signals has been shown to revert the dysfunctional state of exhausted CD8+ T cells in most cases.

Alcohol or truancy may be just a marker of other socially dysfunctional behaviours.

Whether hyperglycemia plays a causal role in this process or is simply a marker of a systemic stress response or of dysfunctional metabolism at the cellular level is not clear.

Clinical failure may also be a marker of severe immunosuppression and a dysfunctional immune system.

The results of our study therefore need to be tested in a large prospective cohort study and compared with group of patients with non-immunological destruction of their salivary glands in order to validate the use of specific salivary changes and dental caries as markers of salivary gland dysfunctional severity/disease severity in pSS.