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Within the centriole, Poc1 shows a precise localization to the microtubule cylinder wall and the proximal/basal cartwheel structure, and is a very early marker for proximal centriole and basal body assembly [3], [6], [7].
The urinary excretion of the cytosolic glutathione S-transferase-A1 (GSTa1-1), a marker for proximal tubule damage, was measured using an ELISA.
Haring et al. [ 9] assessed the use of β2-microglobulin in urine as a marker for proximal tubular damage during FAEs treatment in psoriasis patients.
Kidney injury molecule-1 (KIM-1) is a marker for proximal tubular injury, the hallmark of virtually all proteinuric, toxic and ischemic renal diseases [ 33, 36, 37].
Furthermore, we found that diabetes dramatically induced kidney injury molecule 1 (Kim-1), a marker for proximal tubular injury, and downregulated cubilin, a receptor for albumin uptake (Fig. 2D-G).
Thus, urinary α1-microglobulin is a marker for proximal tubule dysfunction, and increased levels of urinary α1-microglobulin have been reported in patients with type 1/2 diabetes [ 22].
Similar(53)
To test whether the results of RA treatment were due to specific effects on AP patterning or instead due to a more general interference with limb development, we examined a marker for proximal-distal (PD) patterning in mouse and chick limb buds— Hoxa13 (Tamura et al., 1997; Mercader et al., 2000; Yashiro et al., 2004).
TEC were isolated from Immorto mice as described previously [23], labeled with antibodies to neprilsyin/CD10 and aquaporin 4 combinedly, as markers for proximal tubular epithelium [42], [43] and sorted by flow cytometry on a FacsAria cell sorter (BD Biosciences).
For example, known markers for proximal tubules [kidney androgen-regulated protein (kap)] and thick ascending limbs [uromodulin (Umod)] were evidenced in both libraries.
We immunostained inhibitor treated nephrons with markers for proximal, medial, and distal identities (Wt1, Jag1, Cdh1) and measured the size of the domains in which each was expressed.
In the last series of experiments, dual labeling procedures were used to visualize either E-cadherin or N-cadherin and specific markers for proximal and distal nephron segments.
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