This analysis included 997 individuals who had measurements available for oxidized low density lipoprotein (ox-LDL, a marker for oxidative stress) or for the following markers of endothelial damage: soluble intercellular adhesion molecule-1 (sICAM-1), CD40 ligand (CD40L), soluble thrombomodulin (sTM), soluble E-selectin (sESEL) and von Willebrand factor (vWF).
Accordingly, the intracellular marker for oxidative stress, 8-OxoGuo, a widely used marker of RNA oxidation, predicts outcome in patients with type 2 diabetes (26); this marker is also present in patients with HFE (27).
Under conditions of oxidant attack, GSH is rapidly converted to GSSG, making the elevation of the intracellular GSSG/GSH ratio a widely accepted marker for oxidative stress.
Serum 8-OHdG, a marker for oxidative stress that reflects 8-hydroxyguanosine in the DNA, was measured using enzyme-linked immunosorbent assay (ELISA), as previously described52.
These results strengthen the view that δ-ALA-D can be considered a marker for oxidative stress.
Fibrinogen is an abundant plasma protein, highly susceptible to such oxidative modifications, and is therefore a potential marker for oxidative protein damage.
Our data showed that reduced glutathione (GSH) levels, which is a marker for oxidative stress, strikingly decreased with a long-term iron overload in rat kidney.
Our findings suggest that CML modification occurs in vivo and in vitro when oxidative stress from e.g. inflammatory cells is present, indicating that CML may represent a marker for oxidative stress.
The purpose of this study was to compare immunohistochemical expression of heat shock protein-70 (hsp70), a marker for oxidative stress, and 4-hydroxy-2-nonenal adducts (HNE), a marker for lipid peroxidation, in placental villous tissue of normotensive, preeclampsia, and intrauterine growth restricted (IUGR) pregnancies.
ROS generation is a marker for oxidative stress.
Moreover, while increased MPO is associated with ACIC, MPO is also a marker for oxidative stress, and thus may not be specific for ACIC.
