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FGF21 is a valuable marker for diagnostic use of disorders associated with UPRmt.
COMP has been studied as a biological marker for diagnostic and prognostic applications as well as for evaluating treatment effects both in RA and osteoarthritis (OA) [ 12- 17].
Database URL: http://hive.biochemistry.gwu.edu/tools/bioxpress Gene expression is considered a key molecular marker for diagnostic and prognostic assessment of cancer (1 8).
The JAK2 V617F mutation is the most frequent somatic change in myeloproliferative neoplasms, making it an important tumour-specific marker for diagnostic purposes and for the detection of minimal residual disease.
If this marker were used as a binary marker for bladder cancer detection in the general population, it would result in 66% sensitivity and 50% specificity, a poor marker for diagnostic purposes.
The only useful marker for diagnostic tools still is PrPSc [ 37, 38], but its application in an ante-mortem test of prion disease in animals and humans, as proposed by Castilla and collaborators [ 39, 40], with the "Protein Misfolding Cyclic Amplification", is still difficult and no significant results are available yet.
Similar(54)
Excessive production of monoclonal immunoglobulin is a key characteristic and marker for diagnostics of MM.
The selective overexpression of LHRH receptors on human tumors compared to normal tissues makes them a suitable marker for diagnostics, molecular probes and targeted therapeutics.
Perhaps the most challenging aspect of developing a DNA-based marker for diagnostics is identifying unique or distinguishing loci within the target organism to provide a high resolution of detection, perhaps at the pathovar or race level.
Together, these findings not only reveal novel subtype-dependent candidate genes for ASDs, but also identify potential genetic markers for diagnostic screening.
For screening or diagnostic markers For diagnostic (or screening) markers, the data abstraction phase involves an assessment of study quality.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com