Sentence examples for marked morphologic changes from inspiring English sources

Intriguingly, besides growth and invasion defects, marked morphologic changes were observed for the established PRL-3 knockdown cells.

Using microscopy, we found that surviving U2OS and MG63 cells had marked morphologic changes, with a shape resembling dendritic-like cells.

Junction construct transfected EWS502 cells underwent marked morphologic changes in vitro, adopting a round, rather than the elongated phenotype of empty vector transfected counterpart.

In addition, in the case of a multifunctional protein (e.g., Fks1p [35], [35]), detection of the target was difficult even with marked morphologic changes [8].

We found that administration of anti-estrogenic treatment for DCIS resulted in marked morphologic changes, decreased proliferation, and protein expression changes.

MPM can be used to differentiate morphologic changes in rectal carcinomas in patients undergoing preoperative radiochemotherapy.

Furthermore, HCC cells treated with the COX-2 inhibitor celecoxib showed significant reduction of Akt phosphorylation and marked morphologic and biochemical characteristics of apoptosis.

In this scenario, the antibody-accessible β-1,3 glucan could be mostly represented by the glucan bound to the proteins of the outer cell wall, which is likely to undergo even marked variations during growth and morphologic changes, rather than the more invariant β-glucan of the inner cell wall skeleton.

This is accompanied by enlargement and morphologic changes referred to as 'fried egg morphology'.

PC12 morphologic changes and neurite extension consistent with differentiation were visible within 12 hours of NGF addition to the media and became marked over the course of 7 days [See Additional file 1; Figure 1A].

K. Sugimoto et al. (2010a) have also detected and reported these morphologic changes.