Sentence examples for marked in vitro from inspiring English sources

In general, Stachulski and coworkers disclosed that modification of the carbohydrate at 6-O-position of morphine promotes marked in vitro effects on binding to μ opioid receptor subtypes μ1 or μ2 and in vivo antinociceptive activity [6].

MB in model surfactant lipid mixtures showed marked in vitro activity, with spread films exhibiting near-zero minimum surface tension during cycling using captive bubble surfactometry [48].

Phosphatidylinositol-3-phosphate kinase, AKT and dual PI3K-mTOR inhibitors caused marked in vitro enhancement of cytotoxicity induced by HDACIs in HNSCC cancer cells.

However, for multidrug-resistant P. aeruginosa, 3-drug combinations such as that of aztreonam, ceftazidime and amikacin rather than 2-drug combinations were shown to exhibit more marked in vitro antimicrobial effects [ 8, 9].

Colistin had more marked in vitro antimicrobial effects than that of the 3-drug combination against MBL-producing P. aeruginosa, showing bactericidal effects against all 23 strains at 2 24 h after drug addition.

This discrepancy has also been observed in vivo (e.g. [22]) and was even more marked in an in vitro study using another ETA-antagonist [46].

Structural alerts classify another three compounds with activity in vivo but not in vitro (marked in orange).

Epothilones are a novel class of microtubule-stabilising agents, and sagopilone is a fully synthetic epothilone that has shown marked in vivo and in vitro preclinical activity.

In addition, the combination of LAQ824 with trastuzumab induced marked apoptosis in vitro.

Five substances with in vivo mammalian long-term reproductive toxicity are identified in vitro but not from their chemical structures (marked in orange).

In genetics, verification particularly concerns Conformité Européenne (European Conformity; CE -marked in vitro diagnostiCE -marked(inDDs).