Sentence examples for marked effect at from inspiring English sources

We examined the effect of a range of tunicamycin concentrations on hepatocyte viability and found dose related toxicity with minimal effect at 10  μg/ml and marked effect at 20  μg/ml (65% cell death at 24 h, Figure 1a), which was preceded by caspase 3 activation and cytochrome c release at 4 h.

At higher concentrations (⩾10%), agglomeration of HA was observed and this had a marked effect at 20% concentration whereby the presence of nano-HA resulted in fiber breaking.

Loss of Xic1 has a marked effect at later stages of development, resulting in defective cardiac differentiation.

For S. aureus, the addition of vitamin C to the PRE/Cu II) mixture had no significant effect at one equivalent but a marked effect at 5 and 20 equivalents of vitamin C (no detectable growth in either).

Altogether, these data suggest that morbid obesity per se increases C-IMT and F-IMT, with a more marked effect at the carotid arterial site, independently of age, number of CV-RFs, and metabolic status.

Ni2+ inhibits cardiac L-type Ca current (ICa,L) in electrophysiological experiments with a KD of ∼330 530 μM (the higher value with raised cAMP in the pipette dialysate) [26], and produces marked effects at submillimolar concentrations on the magnitude and kinetics of Kv1.5 channel current [27,28] and upon hERG channel activation kinetics [29].

Overall results revealed marked effects in snails caged at various locations, that is, in the different accumulation of metals, which confirmed H. aspersa as a suitable bioindicator for these environmental pollutants (Beeby and Richmond 2002; Dallinger 1994).

The particular α-and γ-subunit isoforms exhibit marked effects on recognition and/or efficacy at the benzodiazepine site.

This hypothesis is underscored by the fact that β-lactam treatment was shown to have marked effects on the capacity to anabolize at least 40% of all sugars investigated.

Intracortical profiling of qT1 along streamlines perpendicular to the cortical mantle revealed marked effects in upper levels that tapered off at the white matter interface.

Another key finding, which supports previous suggestions, is that seasonality in rainfall may have marked effects on R0 and extinction dynamics, even at optimal transmission temperatures.