Sentence examples for marked change of from inspiring English sources

Here we demonstrated that transgenes of Klf-4, c-Myc, Sox2, and Oct4, were persistently expressed in EGFP-positive, iHAC-retained fibroblast clones over three months, and some of these clones exhibited dedifferentiated phenotypes: potent growth ability, marked change of cell morphology, and activation of endogenous pluripotency-related genes.

(7) The marked change of tPA-PAl levels apparently preceded those of MOF score in three out of eight patients and were parallel to them in four out of eight Several important relationships between tPA-PAI and DIC, hypercoagulability, endothelial cell injury, and MODS became evident.

For there has been a marked change of mood in the Netherlands.

Hillary Clinton has admitted that using a personal email account while she was secretary of state "wasn't the best choice", in a marked change of tack.

Still pessimistic, the later Satires show a marked change of tone and some touches of human kindness, as though he had found some consolation at last.

Not so the Eighth, which, after early criticism from the conductor Hermann Levi, underwent patches of reorchestration, abbreviation and in one instance a marked change of character.

In addition, IFN-γ treatment of human MSCs induced marked changes of other KP enzymes at the RNA level (Table 1).

We searched for genes that showed marked changes of expression in the dentate gyrus of Adcyap−/− mice, because PACAP may play a role in schizophrenia and the PAC1 receptor is exclusively expressed in the dentate gyrus of the hippocampus.

Indeed, immunofluorescence staining for BrdU-incorporated cells in skin tissues revealed marked changes of cellular proliferation patterns in the basal layers and hair follicles of RASSF9−/− mice versus WT. (Figure 4A and B).

These may additionally be described with short-term changes, or 'transitions', and marked changes of directions, or 'turning points'.

The study of the two cascades, of ERK and PI3K, confirmed the marked changes of the NGF signaling induced in PC12-27 cells by the expression of p75NTR.