Sentence examples for marked alteration of from inspiring English sources

Notch3 knockout mice (Notch3−/−) showed marked alteration of arterial smooth muscle cells, but no GOM deposition.

In our model, we detected marked alteration of both these proteins.

Histologic examination showed marked alteration of the intestinal mucosa: erosions, villi depletion, and hemorrhagic infiltration.

Notch3 knockout mice (Notch3−/−) show marked alteration of arterial SMCs, pointing to a critical role of Notch3 in the maturation and maintenance of arteries (Joutel, 2010a).

In addition, the treatment with PNGase F resulted in a marked alteration of electrophoretic mobility.

In conclusion, in this study, we report that the gain-of-function EPOR G1251T mutation results in a marked alteration of growth and differentiation of human CD34+ and in an increase of erythroid progenitors' surface EPOR peptide.

Our results suggest a new model of skin aging in which marked alterations of Fp may affect the histological characteristics of skin.

In comparison to body site-specific controls, we detected marked alterations of lipid contents and composition, especially of ceramides, in lesional and non-lesional skin of atopic dogs.

Patients with coronary artery disease and DM type 2 showed marked alterations of metabolic, hemostatic, fibrinolytic and rheologic parameters, which can produce a prothrombogenic state.

Progression of fibrosis upon sustained liver insult is associated with expansion of fibrotic septa, ultimately leading to cirrhosis, which is a condition defined by fibrotic septa surrounding regenerating nodules and marked alterations of hepatic vascularisation.

Therefore, under the low reproductive hormone levels of hpg mice, immunostaining revealed marked alterations to the maturation of both female and male AVPV kisspeptin populations.