Sentence examples for map the epitope from inspiring English sources

We map the epitope of the broadly neutralizing anti-gp120 antibody VRC01 using both a random mutagenesis library and a defined mutant panel and find that the resultant epitope maps are consistent with one another and with the crystallographically identified contact residues.

A peptide array (PepStar; JPT, Berlin, Germany) was used to map the epitope of the anti-VEGF-C antibody.

Attempts to map the epitope by Pepscan analysis using overlapping linear peptides were unsuccessful (not shown), consistent with HJ16 recognition of a discontinuous epitope.

To map the epitope, we tested HK20 against all overlapping 15-mer peptides of the extracellular region of HIV-1 gp41.

In this case we chose to map the epitope sequences reported by Yu and co-authors [ 42].

The third approach taken to map the epitope(s) was to make a series of TNFα mutants (n=20) (Table 1).

Here, we describe a method to precisely and efficiently map the epitopes of a panel of antibodies in parallel over the course of several weeks.

It will be important in future studies to map the epitopes in EBNA-1 that lead to the cross-reactivity with dsDNA and determine whether or not these epitopes are conformational.

A number of approaches were taken to map the epitopes recognized by AZD9773.

17 Next, we compared the performance of the EpiSearch method to map the epitopes recognized by mAb Bo2C11 on the C2 domain of coagulation factor VIII (FVIII).

A high-throughput alanine scanning shotgun mutagenesis strategy was used to map the epitopes of several conformation-dependent mAbs on CCR5.