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Many proteins within these bodies contain KH or RRM RNA-binding domains as well as low complexity (LC) sequences of unknown function.
Surprisingly, the function of many proteins within this compartment has not been experimentally addressed.
The likelihood network reveals that diverse data sources connect many proteins within the cluster with high SWC scores.
We consider it likely that such phenomena of coupled binding are important in localizing many proteins within RNPs.
PDZ-containing proteins interact with many proteins within cells, so studying the regulatory mechanisms of PDZ protein-protein interactions, such as phosphorylation, autoinhibition, and allostery, is also vital to understand their biology.
Some genes, particularly those with longer 3′ UTRs, are often the targets of multiple miRNAs and consequently, miRNA mediated regulation tends to result in the fine tuning of the expression of many proteins within a cell [ 1, 2].
Similar(54)
Many proteins function within large multimeric complexes that are highly dosage dependent.
There have been many proteins identified within breast cancer EVs that give insight into the nature and severity of the disease.
Many proteins found within the INB are not known to be involved in the DNA damage response or chromatin organisation, such as SF2 or CRM1.
As noted earlier, many proteins encoded within introns in organellar genomes are initially translated as fusions with upstream exon sequences, requiring subsequent proteolytic processing to provide an active protein with an amino terminus in domain IV [ 40, 41, 66].
In addition to their effects on cell behavior, PDGF and IFN-γ interact with many proteins and proteoglycans within tissues.
Related(20)
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