Sentence examples for many basic residues from inspiring English sources

hLF contains many basic residues, and thus we used cation-exchange chromatography to purify rhLF.

This prong is surrounded by many basic residues that are also conserved in Syndapin homologues (K127, K130, H120, H121, R129, K28, K137, K35, K112; Figure 2C and S1).

The charge distribution of Skp is notable, with many basic residues clustered around the tips of the α-helical tentacles resulting in a large macrodipole moment [103,104].

Without a priori knowledge of which hTERT residues interact with TEL-patch, we chose to mutate as many basic residues as we reasonably could.

Analysis of PYD-containing proteins indicated that the α3 helix is directly involved in PYD PYD interactions, whereas the α6 helix is the most variable in length and sequence (Jin et al. 2013); the α5 helix comprises many basic residues, some of which are highly exposed at the protein surface.

However, in alignments of known HMG boxes a loose consensus sequence can be defined, in which many basic and aromatic residues are conserved [ 24- 26] (see also Fig. 4B).

The PRH C-terminal domain is composed of almost four times as many acidic residues as basic residues [ 1] and has been shown to be involved in transcriptional activation of the bile transporter gene NTCP (sodium-dependent bile acid co-transporter) [ 30].

DOI: http://dx.doi.org/10.7554/eLife.06585.004 Conserved acidic residues near the amino terminus of actin create an electronegative patch on the surface of actin filaments that interacts with positively charged, basic residues in many actin binding proteins (Fujii et al., 2010).

Interestingly, Mth10b has many more acidic amino acid residues than basic residues, and its isoelectric point is only 4.56 (Table 1), which is inconsistent with the characteristics of a nucleic acid-binding protein.

Finally, we report that many of the sequences contain not simply early basic residues but contain Met-Lys as the first two residues in the protein sequence.

Structural analysis revealed that many highly reactive sites exist within clusters of basic residues, whereas lysines that show low reactivity are engaged in strong attractive electrostatic interactions with acidic residues.