Sentence examples for multiple basic residues from inspiring English sources
These PCs cleave their protein substrates very specifically following multiple basic residues.
While cytosolic peptide degradation is generally extremely rapid, some peptides, for example those with multiple basic residues in the aminoterminal positions, have been found to be more resistant to degradation [15], [28].
The cleavage sites of all known virulent strains of NDV have multiple basic residues (bold and underlined) that contain the preferred cleavage site of the intracellular cellular protease furin (R-X-K/R-R↓F) present in most cell types.
PPARγ has multiple basic residues that allow pairing with the acidic sulfhydryl group of DOSS, potentially allowing hydrogen bonding between the ligand and receptor.
In contrast to RhoE phosphorylation sites, these optimised substrates feature multiple basic residues N-terminal to the phosphoacceptor site (Supplementary Figure S4B).
The contribution of electrostatic interactions to the binding of RPA32C targets is evident from the charge complementarity of the acidic RPA32C binding surface and the presence of multiple basic residues in the target binding motifs.
Such an unstructured region with multiple highly basic residues, which has been implicated in binding to other factors [50], would be particularly susceptible to charging.
The switch from an LPAI virus to an HPAI virus phenotype is achieved mainly by introduction of multiple basic amino acid residues into the hemagglutinin cleavage site.
The HA protein of the H5N2qd14 virus has multiple basic amino acid residues (PQIEGRRRKR↓GLF) at the cleavage site, categorizing it as an HPAI virus.
A short sequence containing multiple basic amino acid residues has been proposed to contribute to recruitment of proteins to membrane sub-regions and to function in receptor-internalization via interaction with phospholipids [ 84- 86].
Thrombin mutants with multiple alanine substitution of basic residues showed a progressively greater defect in inhibition potency.
