After prediction, experienced annotators manually annotated the predicted protein complexes according to our standardized procedures, using literature mining and the wealth of annotation data in the human full-length cDNA database "H-Invitational Database" (H-InvDB) that we developed [ 18- 20].
To establish uniform annotation procedures, we manually annotated the RNA genes first because they provided a manageable number of genes to complete and are highly conserved across species [7].
Based on this annotation of the raw images, we manually annotated the flux-tensor based segmentation by coloring the segments using a simple drawing program.
To evaluate the performance of each crack detector, we manually annotated the crack pixels in each image.
Because of the fact that silences were not manually annotated, the transcriptions were extended by passing the signal through the hierarchical audio segmentation described in[17].
Thus, we manually annotated the video of Acheulean and Oldowan tool making sequences at subsecond precision with the help of ethogram-production software (Etholog, [62]).
