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Alignments were manually adjusted as needed.
Sequences were aligned using ClustalW [ 77] and Tcoffee software [ 78] and manually adjusted as needed.
Alignments were subsequently manually adjusted as necessary when sequences with variable-length helices and/or loops were added.
The quality of PET/CT co-registration, which can be compromised by patient movement, was visually assessed and VOIs were manually adjusted as required.
Some parameters were manually adjusted as follows: the motif limit to 20, the minimum motif width to 6, the minimum number of sites for each motif to 6, and the e-value threshold to 0.1.
Whole-genome alignment was needed to show genomic context, but in practice Mugsy aligned some locus boundaries incorrectly, so its results were manually adjusted as described in the Methods.
Similar(51)
The images were manually checked, and the contour, and/or threshold level could be adjusted as necessary.
The resulting alignment was then manually adjusted so as to align the conserved helicase motifs.
While all parameters can be manually adjusted, this becomes impractical as the number of compartments N in the model increases, since the total number of parameters is 4×N.
The HMMs were created using HMMER3, with manually adjusted alignments of representative sequences as seed.
It is made of sheet steel, as are the numbers that are manually adjusted by operator Darryl Willson to reflect the scores of the games going on at any one time in the National and American Leagues during Cubs baseball games.
Related(18)
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manually labeled as
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