Sentence examples for manner the activity from inspiring English sources

The sulfhydryl reactive reagent 2- trimethylammonium)ethyl methanethiosulfonate bromide (MTSET) alters in a phosphorylation-dependent manner the activity of channels containing single cysteine residues that are engineered into the short intracellular loop connecting membrane α-helices H and I (H-I loop), the AD, CBS1, and CBS2- trimethylammonium

None of the dementia peptides compromise in any significant manner the activity of HSP-70 (Figure S3).

Changes in the accumulation of manganese in target nuclei reflect in a fairly direct manner the activity of the neurons where manganese was introduced and taken up.

It is well known that the tumour microenvironment plays an important role in the pathogenesis of prostate cancer [63], and it can be hypothesised that a component of the tumour microenvironment regulates in the same manner the activity of both CB1 receptors and FAAH.

Neither of these agents was able to restore, in a significant manner, the activity of the oxidant-treated enzyme under these conditions (results not shown).

The core idea underpinning reflective practice is that humans have the capacity to consider in introspective manner, the activities that they are engaged in and then moderate their future activities, which means that reflective practice helps 'deep' learning take place [ 49].

As shown in Figure 2A, the ability of PI3K to generate PIP3 decreased after S9 treatment in a concentration-dependent manner and the activity decreased to 53.2% in the presence of 1 µM S9.

On the other hand, in somatic cells, maintenance of DNA methylation during DNA replication is carried out in a semi-conservative manner by the activity of DNMT1, which shows a higher affinity to hemimethylated DNA template and is physically associated with PCNA in the replication fork [1], [5].

Generally, HIF-1α is degraded in an oxygen-dependent manner through the activity of PHD2 enzyme, which hydroxylates HIF-1α on proline residues 402 and 564, and this hydroxylated form is bound by the E3 ubiquitin ligase VHL which promotes HIF-1α ubiquitination and its subsequent proteasomal degradation [19].

The hydrolysis of the ATP in a DNA-replication dependent manner decreases the activity of the protein after initiation has taken place, thus reducing the probability that a new initiation event will occur within the same cell cycle [ 24, 25].

The predicted target of miR-210, Tcf7l2 was repressed at the transcriptional level in a dose-dependent manner, and the activity of luciferase reporter containing the miR-210 binding site in the 3'UTR of Tcf7l2 mRNA decreased for nearly 60% in HEK293FT cells.