Sentence examples for manifested as severe from inspiring English sources

Background & Aims: Peutz Jeghers syndrome (PJS) is typically manifested as severe gastrointestinal polyposis.

To describe an unusual presentation of ring chromosome 12, which manifested as severe azoospermia, resulting in male infertility.

This acute DA deficiency results in the development of a pronounced behavioral phenotype manifested as severe akinesia and rigidity.

In some herds, the disease may also be manifested as severe haemorrhagic diarrhoea with high mortality rates [ 3].

Burkholderia pseudomallei is an emerging, highly pathogenic, Gram-negative betaproteobacterium that causes melioidosis, a potentially serious and fatal disease often manifested as severe community-acquired pneumonia and sepsis.

Free DOX had a relatively short half-life for elimination (t1/2 β) of 3.13 h and a small AUC0→∞ value of 6.27  μg/mL/h, which was a consequence of its low bioavailability and necessitates a larger or more frequent clinical dose to obtain a better therapy index, even though such dosing carries with it a greater risk for toxicity manifested as severe side effects [ 21].

Acute aortic dissection is in 80%% of cases first manifested as sudden extremely severe pain.

This reaction results in unstable intermediates, damaging the tissue, which manifests as severe hepatotoxicity [ 4].

Acute muscle strain injuries manifest as severe disruption at the musculotendinous junction (MTJ) primarily in biarticular muscles [ 1, 4].

Additional neurological signs like circling to the left and behavioural changes manifesting as severe aggression were present.

Although gingival lesions are uncommon at the onset, they usually manifest as severe desquamative or erosive gingivitis in advanced stages of PV [ 86].