Enchondromas are benign but tend to have high cellularity, enlarged nuclei and double-nucleated cells making differentiation between benign tumours and malign lesions like chondrosarcomas difficult.
Septin2 was excluded due to a high level of sequence similarity to other Septin family members, making differentiation between different septins in divergent organisms difficult.
These findings indicate that the KL-6 concentration of pancreatic juice is clinically useful when PJC specimens are inadequate, making differentiation between malignant and benign conditions difficult.
Moreover, retrograde transsynaptic atrophy may occur, making differentiation between CVI and visual impairment due to optic atrophy in these disorders difficult.
Although HUS patients are, typically, young children with a history of diarrhea and acute renal failure, the clinical manifestations of HUS and TTP often overlap, making differentiation between the two syndromes based solely on clinical presentation difficult.
The APP response is similar to what has been observed earlier during viral and bacterial respiratory diseases making differentiation between lungworm infection and those other respiratory infections not possible based solely on measurements of the APP response.
