Sentence examples for majority of causative from inspiring English sources

The emergence of antimicrobial resistance is of particular concern with respect to urinary tract infections, since the majority of causative agents are Gram-negative bacteria.

The majority of causative microbes of DNM are Streptococci and oral anaerobes.

The majority of causative microbes of DNM are the same as those of oropharyngeal infections; i.e., Streptococci and oral anaerobes [ 2].

The majority of causative variants identified so far in Mendelian disease have been found in coding regions (Botstein and Risch 2003), although ascertainment bias is likely to play a role in this conclusion.

The majority of causative SCN4A mutations are missense, gain of function mutations (Tsujino et al., 2003; Jurkat-Rott et al., 2010; Lossin et al., 2012), and are usually located within the pore forming segments S5 S6, the voltage sensor segment S4 or the S4 S5 linker of the Nav1.4 channel.

The majority of clearly causative mutations were in genes already known to cause EE, including SCN1A, STXBP1, and CDKL5, but two new disease genes emerged: GABRB3 and ALG13.

The majority of the causative mutations expected (8 out of 11 LHON-causing mutations) on the LHON dataset was recognized as affecting function by the application of the whole stepwise prioritization workflow with the exception of the mutations m.3700G>A (MT- ND1), m.14502T>C (MT- ND6) and m.14484T>C (MT- ND6) (Supplementary Table 1).

The majority of the causative sequence variants identified clustered at the C-terminal end of the gene in exon 18, as documented previously.

Malignant hyperthermia (MH) is a fulminant pharmacogenetic disorder in which the vast majority of identified causative mutations are found in the genes encoding RyR1 [ 8, 9] or CaV1.1 [ 10– 13].

However, in the majority of episodes the causative pathogen could not be isolated.

The workflow was validated on mitochondrial sequences from Leber's Hereditary Optic Neuropathy affected individuals, successfully identifying 23 variants including the majority of the known causative ones.