Sentence examples for major reprogramming of from inspiring English sources

The mammalian genome undergoes major reprogramming of modification patterns in germ cells and in the early embryo.

This suggests that no major reprogramming of transcription patterns occurs at the end of the ripening.

Exogenous application of MeJA results in major reprogramming of defensive gene expression in plants, inducing induction of chemical defenses, and effects similar to the ones induced by mechanical or herbivore damaged plants [ 27, 28, 32].

EMT is a complex, stepwise phenomenon that occurs during embryonic development and tumor progression and involves major reprogramming of gene expression that leads to alterations in cell fate and behavior.

Although improved contractile function during shPLB therapy results immediately from its influence on excitation contraction coupling via the cytoplasmic Ca2+ transients, the marked reduction of LV hypertrophy and dilation is not deduced as easily, because it involves major reprogramming of the cardiac transcriptome.

This kind of memory has now been demonstrated in each of the major reprogramming methodologies.

A comparison of the temporal profiles of these genes revealed dynamic transcript accumulation profiles with major reprogramming events that occurred during the time intervals of 80-120 220-240°Cdays 220-240°Cdays

These findings suggested that a major reprogramming had occurred in the metabolic pathways of the cells.

The next major reprogramming process occurs in the cells that will form the germ line of the developing embryo to achieve an epigenetic state distinct from somatic cells.

Analysis of gene expression in TA-habituated cells using an Affymetrix GeneChip Poplar Genome Array revealed that durable resistance to TA is associated with a major and complex reprogramming of gene expression implicating processes such as cell wall synthesis and modification, lignin and flavonoid synthesis, as well as DNA and chromatin modifications.

The third major advance was the reprogramming of adult cells to induced pluripotent stem cells (iPSCs), described by Yamanaka and co-workers [ 14, 15].