Sentence examples for major randomized clinical from inspiring English sources

A literature search revealed 9 major randomized clinical trials published to date.

Since the NCDS, the HEMO Study was the first major randomized clinical trial designed to study the effect of dose of dialysis and dialyzer flux on patient outcomes.

Because these patients were excluded from major randomized clinical trials of neurohormonal blockade in HF there is little evidence about their role in HF PEF.

I know that there are currently two major randomized clinical trials in preparation.

In contrast, none of the major randomized clinical trials from 2001 and 2002, which are part of current guidelines, are cited.

Analysis of available evidence from clinical trials clearly indicates that there is enough uncertainty regarding the risk-to-benefit ratio of treatment of anemic CKD patients with ESA to warrant additional major randomized clinical trials (66).

The DCCT was a major prospective, randomized clinical trial that evaluated the effect of glycemic control on long-term DM complications (68).

A major differentiating factor in randomized clinical trials showing benefit on clinical outcome from reaching goal nutrition delivery (Table 2) versus trials not demonstrating a benefit of reaching goal nutrition is that all trials showing benefit on clinical outcomes reached a protein delivery of >1.0 g/kg/day in the higher nutrition delivery group.

The major reason why controlled randomized clinical studies fail to show an existing effect is inadequate statistical power, caused by high drop-out rates, insufficient patient numbers in the intervention and control group to show an effect of a given size, or high placebo responses [ 48, 64].

3. Target volume definition and dosimetric characteristics of the two ongoing randomized clinical trials have major methodological and technical differences, which will make local results uncomparable.

Recent randomized clinical trials and a major meta-analysis have emphasized the importance of LDL-cholesterol (LDL-C) lowering for cardiovascular risk reduction in diabetes mellitus [1] [3].