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The phrase "major diseases" is correct and usable in written English.
You can use it when referring to a large group of diseases that are serious and/or widespread. For example, "The World Health Organization is working to develop vaccines for major diseases such as malaria, HIV, and tuberculosis."
Exact(60)
"Where do the major diseases come from?
Ebola also highlights the cost of not acting strategically against major diseases.
A happy medical mystery: a declining incidence of major diseases in wealthy countries.
And the public efforts to halt major diseases have been remarkable.
Malaria is often mistaken for pneumonia, meningitis and other major diseases.
Their report reflects a growing medical interest in understanding differences in the way major diseases affect men and women.
Some might be cheap diagnostic tests and effective but relatively inexpensive vaccines or treatments for major diseases.
For that, you get a phone that has some new features, none of which cures major diseases or painful inflammation.
For the first time ever, we are looking at the chance to cure major diseases, possibly before they take hold.
In the last few months, studies using whole genome association have identified genes or genetic elements involved in at least 10 major diseases.
Last year, the school enlarged its incoming class, hoping more students would specialize in the major diseases and preventative care, he said.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com