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Discover Ludwig"major illness" is a correct and usable phrase in written English.
It is used to describe a serious and significant health condition or disease. You can use it in a sentence when talking about someone's health or a medical diagnosis. Example: Due to her major illness, she had to take a leave of absence from work and focus on her treatment.
Exact(57)
Sadness is normal, but depression is a major illness.
A small amount of the rare bacteria can cause major illness.
Prostate hyperplasia and neoplasia are major illness of men and elderly dogs.
Significant regression occurred in 6/14, following acute metabolic decompensation or major illness.
Extensions for major illness or family emergency do not count against this entitlement.
A. Although it's not a major illness, excessive sweating is far from trivial.
Their philosophy is, it could be worse, and other than major illness or death, everything else is interesting.
But that won't cover major illness and the women do not spend it on themselves, saving it for their children.
Similar(3)
In such cases, the household may report the condition as a 'major illness'.
This survey aimed at identifying households with a 'major illness' among the rural Cambodia's population for further in-depth investigation.
Personal distractions include major illness/injuries as well as winning major national or international awards.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com